Layer-by-layer polymer coating on discrete particles of cubic lyotropic liquid crystalline dispersions (cubosomes)

CD Driever; X Mulet; LJ Waddington; A Postma; H Thissen; F Caruso; CJ Drummond

Journal article

Layer-by-layer polymer coating on discrete particles of cubic lyotropic liquid crystalline dispersions (cubosomes)

CD Driever, X Mulet, LJ Waddington, A Postma, H Thissen, F Caruso, CJ Drummond

Langmuir | AMER CHEMICAL SOC | Published : 2013

DOI: 10.1021/la401660h

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Abstract

Cubic phase lyotropic liquid crystalline colloidal dispersions (cubosomes) were surface-modified with seven polyelectrolyte layers using a layer-by-layer (LbL) approach. The first layer consisted of a copolymer synthesized from methacrylic acid and oleoyl methacrylate for enhanced incorporation within the bilayer of the cubic nanostructure. Six additional layers of poly(l-lysine) and poly(methacrylic acid) were then sequentially added, followed by a washing procedure to remove polymer aggregates from the soft matter particles. Polymer buildup was monitored via microelectrophoresis, dynamic light scattering, and small-angle X-ray scattering. Polymer-coated cubosomes were observed with cryo-tr..

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Frank Caruso Author

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Funding Acknowledgements

This research was undertaken, in part, on the Small Angle X-ray Scattering beamline at the Australian Synchrotron, Victoria, Australia. This work was supported by the Australian Research Council under the Australian Laureate Fellowship (F.C., 120100030). X.M. was the recipient of a CSIRO-Monash University Collaborative Research Post-Doctoral Fellowship.